정승민 교수
Jeong, Seung Min
연구분야
노화, 대사기전
연구키워드
노화기전
역노화
섬유화
암대사
교수소개
정승민 교수는 서울대학교 분자생물학과에서 학사학위를, 같은 대학 생명과학부에서 박사학위를 취득하였다. 이후 미국 Harvard Medical School에서 박사후연구원으로 근무하였다. 2015년부터 가톨릭대학교 의과대학 생화학교실에 재직 중이며, 현재 ‘노화 및 대사질환 연구소’ 연구소장 직을 맡고 있다. 주요 연구 분야는 노화의 분자적 기전, 섬유화 등 노화 관련 질환이다.
연구실적
-
2025.12 |
교신저자 |
ANIMAL CELLS AND SYSTEMS,
제29권
1호
, pp.512-522
RNA binding protein HuD regulates fatty acid oxidation in pancreatic β-cells by modulating long-chain acyl-CoA dehydrogenase expression -
2025.11 |
공동저자 |
CANCER RESEARCH,
제85권
22호
, pp.4398-4414
Condensation of the Golgi Apparatus Activates YAP1 to Promote Gastric Cancer Progression -
2024.11 |
교신저자 |
CANCER GENOMICS & PROTEOMICS,
제21권
6호
, pp.622-629
SF3B4 Regulates Cellular Senescence and Suppresses Therapy-induced Senescence of Cancer Cells -
2024.08 |
교신저자 |
MOLECULES AND CELLS,
제47권
8호
, pp.100096-100096
Targeting cellular adaptive responses to glutaminolysis perturbation for cancer therapy -
2024.06 |
공동저자 |
CELL DEATH & DISEASE,
제15권
6호
, pp.404-404
The miR-30-5p/TIA-1 axis directs cellular senescence by regulating mitochondrial dynamics -
2024.03 |
교신저자 |
ADVANCED SCIENCE,
제11권
10호
, pp.2304702-2304702
Induction of Fatty Acid Oxidation Underlies DNA Damage-Induced Cell Death and Ameliorates Obesity-Driven Chemoresistance -
2023.12 |
교신저자 |
BMB REPORTS,
제56권
12호
, pp.651-656
Fatty acid oxidation regulates cellular senescence by modulating the autophagy-SIRT1 axis -
2023.09 |
교신저자 |
ONCOGENE,
제42권
38호
, pp.2828-2840
YAP governs cellular adaptation to perturbation of glutamine metabolism by regulating ATF4-mediated stress response -
2023.09 |
교신저자 |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,
제674권
, pp.124-132
Fatty acid oxidation supports melanoma cell migration through autophagy regulation -
2023.07 |
교신저자 |
CELL DEATH & DISEASE,
제14권
7호
, pp.435-435
Fatty acid oxidation facilitates DNA double-strand break repair by promoting PARP1 acetylation -
2023.06 |
교신저자 |
CANCER GENE THERAPY,
제30권
6호
, pp.878-889
Suppression of fatty acid oxidation supports pancreatic cancer growth and survival under hypoxic conditions through autophagy induction -
2022.12 |
공동저자 |
CELL DEATH & DISEASE,
제13권
12호
, pp.1019-1019
RNA binding protein HuD mediates the crosstalk between β cells and islet endothelial cells by the regulation of Endostatin and Serpin E1 expression -
2022.11 |
제1저자 |
BIOCHIMICA ET BIOPHYSICA ACTA - REVIEWS ON CANCER,
제1877권
6호
, pp.188824-188824
Targeting Cdc20 for cancer therapy -
2022.04 |
공동저자 |
CELL DEATH & DISEASE,
제13권
4호
, pp.329-329
Loss of RNA binding protein HuD facilitates the production of the senescence-associated secretory phenotype -
2021.12 |
교신저자 |
CELL DEATH DISCOVERY,
제7권
1호
, pp.395-395
Mitochondrial glutamine metabolism regulates sensitivity of cancer cells after chemotherapy via amphiregulin -
2021.07 |
공동저자 |
ONCOGENE,
제40권
28호
, pp.4652-4662
SMARCA4 oncogenic potential via IRAK1 enhancer to activate Gankyrin and AKR1B10 in liver cancer -
2021.05 |
공동저자 |
STEM CELL RESEARCH,
제53권
0호
, pp.102321-102321
Generation of Brachyury-mCherry knock-in reporter human pluripotent stem cell line (SNUe003-A-2) using CRISPR/CAS9 nuclease -
2020.12 |
교신저자 |
ANTICANCER RESEARCH,
제40권
12호
, pp.6891-6897
Mitochondrial Glutamine Metabolism Determines Senescence Induction After Chemotherapy -
2020.09 |
공동저자 |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,
제530권
0호
, pp.266-272
The RNA-binding protein, HuD regulates proglucagon biosynthesis in pancreatic alpha cells -
2019.06 |
교신저자 |
ONCOGENE,
제38권
24호
, pp.4729-4738
Mitochondrial GPT2 plays a pivotal role in metabolic adaptation to the perturbation of mitochondrial glutamine metabolism -
2019.05 |
제1저자 |
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY,
제73권
0호
, pp.87-94
Dye encapsulated polymeric nanoprobes for in vitro and in vivo fluorescence imaging in panchromatic range -
2018.07 |
공동저자 |
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,
제115권
27호
, pp.7057-7062
Inhibition of epithelial cell migration and Src/FAK signaling by SIRT3 -
2018.06 |
교신저자 |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,
제501권
3호
, pp.739-744
PGC1α is required for the induction of contact inhibition by suppressing ROS -
2018.02 |
교신저자 |
CELL DEATH & DISEASE,
제9권
2호
, pp.55-55
Mitochondrial glutamine metabolism via GOT2 supports pancreatic cancer growth through senescence inhibition -
2017.03 |
공동저자 |
MOLECULAR & CELLULAR TOXICOLOGY,
제13권
1호
, pp.95-103
BIS overexpression does not affect the sensitivity of HEK 293T cells against apoptosis -
2016.08 |
교신저자 |
SCIENTIFIC REPORTS,
제6권
0호
, pp.30767-30767
Enhanced mitochondrial glutamine anaplerosis suppresses pancreatic cancer growth through autophagy inhibition -
2016.03 |
교신저자 |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,
제471권
3호
, pp.373-379
Transferrin receptor regulates pancreatic cancer growth by modulating mitochondrial respiration and ROS generation -
2016.02 |
교신저자 |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,
제470권
2호
, pp.251-256
SIRT4 regulates cancer cell survival and growth after stress -
2015.09 |
교신저자 |
MOLECULES AND CELLS,
제38권
9호
, pp.750-758
Sirtuins in Cancer: a Balancing Act between Genome Stability and Metabolism
- 2016.01 | 제7회 생화학분자생물학회 동계학술대회 | 국내학술대회(구연)
Regulation of metabolic stress response in pancreatic cancer therapy - 2015.12 | 2015 한국분자세포생물학회 마우스유전체분과 심포지움 | 국내학술대회(구연)
Regulation of metabolic stress response in pancreatic cancer therapy - 2015.09 | The 27th International conference of the Korean society for molecular and cellular biology | 국제학술대회(구연)
The role of mitochondrial glutamine metabolism in progression and therapeutic resistance of cancers - 2015.05 | 제23회 기초의학 학술대회 | 국내학술대회(구연)
Regulation of Cellular Metabolic Stress Response